Irritable Bowel Syndrome
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Amitiza Dosage

The recommended Amitiza dosage for treating chronic idiopathic constipation in men and women is 24 mcg twice daily. For women who are using the drug for treating irritable bowel syndrome with constipation, the recommended dose is 8 mcg twice daily. You should take your dose of Amitiza with food and water. It is also important to swallow the capsule whole, and not chew or open it.

Amitiza Dosage: An Introduction

The dose of Amitiza® (lubiprostone) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The medical condition being treated
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Dose of Amitiza for IBS

The recommended Amitiza dose for treating irritable bowel syndrome (IBS) with constipation in women is Amitiza 8 mcg twice daily with food and water. This medication is not approved for treating irritable bowel syndrome in men, as it has not yet been shown to be effective.
 

Amitiza Dosing for Constipation

The recommended Amitiza dose for treating chronic idiopathic constipation (long-term constipation with no known cause) is Amitiza 24 mcg twice daily with food and water. The medication is approved for both men and women for this use.
 

General Information on Your Amitiza Dosage

Some considerations for people taking Amitiza include the following:
 
  • The medication comes in capsule form. It is usually taken by mouth twice daily with food and water.
     
  • Make sure to swallow the capsules whole. Do not chew or open them.
     
  • For the medication to work properly, it must be taken as prescribed. Amitiza will not continue to work if you stop taking it.
     
  • If you are unsure about anything related to your dosage or Amitiza dosing in general, please talk with your doctor, nurse, or pharmacist.
     
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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