Amitiza Dosage

The recommended Amitiza dosage for treating chronic idiopathic constipation in men and women is 24 mcg twice daily. For women who are using the drug for treating irritable bowel syndrome with constipation, the recommended dose is 8 mcg twice daily. You should take your dose of Amitiza with food and water. It is also important to swallow the capsule whole, and not chew or open it.

Amitiza Dosage: An Introduction

The dose of Amitiza® (lubiprostone) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The medical condition being treated
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Dose of Amitiza for IBS

The recommended Amitiza dose for treating irritable bowel syndrome (IBS) with constipation in women is Amitiza 8 mcg twice daily with food and water. This medication is not approved for treating irritable bowel syndrome in men, as it has not yet been shown to be effective. In people with impaired liver function, your dose may need to be reduced. For severe liver impairment, the recommended dose is 8 mcg once daily. Your healthcare provider will monitor your response and adjust accordingly.
 

Amitiza Dosing for Constipation

The recommended Amitiza dose for treating chronic idiopathic constipation (long-term constipation with no known cause) or constipation due to chronic opioid pain medication use is Amitiza 24 mcg twice daily with food and water. The medication is approved for both men and women for these uses. 
 
In people with impaired liver function, your dose may need to be reduced. For moderate liver impairment, the recommended dose is 16 mcg twice daily. The recommended dose for severe liver impairment is 8 mcg twice daily. Your healthcare provider will monitor your response and adjust accordingly.
 
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Amitiza Medication Information

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