Is Lotronex Safe?
Lotronex® (alosetron hydrochloride) is a medication prescribed to help treat severe diarrhea associated with irritable bowel syndrome (IBS) in women. It is only prescribed when other treatments have been tried but have not adequately controlled IBS symptoms. Although this can be an effective treatment, Lotronex is not safe for some people.
This medication has some potentially dangerous and even life-threatening complications associated with it. In fact, Lotronex can only be obtained through a restricted-use program. Lotronex can cause serious bowel complications, such as a blockage, tearing, and a life-threatening condition known as toxic megacolon (when the intestines become abnormally wide).
Because of these and other complications that may occur, you can only obtain Lotronex if you meet certain criteria and after you have reviewed specific guidelines on the risks associated with this drug.
(Click Lotronex Warnings and Precautions for a more detailed look at whether Lotronex is safe and when it should be avoided. This article also lists other serious complications that may occur with this drug.)