Your healthcare provider will determine an appropriate dosage of Lotronex based on how you respond to this drug, whether you develop side effects, and various other factors. The usual starting amount to treat diarrhea-predominant irritable bowel syndrome is 0.5 mg taken twice daily. However, if you develop side effects or become constipated, you may need a lower dose.
An Introduction to Dosing With Lotronex
The dose of Lotronex® (alosetron hydrochloride) your healthcare provider recommends may vary, depending on a few factors, including:
- How you respond to it
- Side effects you develop
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
What Is the Recommended Lotronex Dosage?
The standard initial Lotronex dosage for treating diarrhea-predominant irritable bowel syndrome (IBS) is 0.5 mg twice a day. You will continue to take this dosage for at least four weeks to see how you respond to the medicine, and make sure you tolerate it well. If you become constipated, your amount will need to be reduced to 0.5 mg once a day.
If your symptoms are well controlled after four weeks, and you did not develop constipation or other side effects, you will be maintained on your current dose. If, however, your symptoms are not adequately controlled, and you tolerated the medication, your healthcare provider may choose to increase your dose to a maximum of 1 mg twice a day.
If you become constipated during treatment, you should stop taking Lotronex and contact your healthcare provider. Lotronex has been reported to cause serious, potentially life-threatening constipation-related problems.
People who have taken Lotronex 1 mg twice daily for 4 weeks, and whose symptoms are still not adequately controlled, should stop taking the medicine and contact their healthcare provider. Lotronex might not be the best medication for them.