Women who have severe diarrhea associated with irritable bowel syndrome (IBS) may benefit from using a drug called Lotronex® (alosetron hydrochloride). However, this medication is not suitable for everyone, so it's important to review the safety information for Lotronex with your healthcare provider before starting treatment. For example, make sure he or she is aware of any other health conditions you may have, such as a blood-clotting problem, diverticulitis, or liver disease.
Lotronex comes in the form of a tablet that is taken once or twice a day. Side effects that may occur with this medicine include constipation, nausea, and abdominal (stomach) pain.
(For more information on this medication, click Lotronex. This full-length article includes details on safety warnings, how the drug works, dosing instructions, and more.)
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: ArthurSchoenstadt, MD
List of references (click here):
Lotronex [package insert]. San Diego, CA: Prometheus Laboratories, Inc.;2010 September.
Lotronex Web site. Available at: http://www.lotronex.com/. Accessed May 5, 2013.
United States Food and Drug Administration (FDA). Questions and answers about Lotronex (June 7, 2002). FDA Web site. Available at: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm110859.htm. Accessed May 5, 2013.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed May 4, 2013.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
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