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Zelnorm and Depression

There are some potential side effects associated with the use of Zelnorm, and depression is one that occurs rarely (in less than 1 percent of people). Given how rarely depression occurs in people taking Zelnorm and how common it is in the general population, it is unknown whether Zelnorm actually causes depression. If you develop symptoms of depression (such as feelings of hopelessness and pessimism or thoughts of death or suicide) while taking Zelnorm, let your healthcare provider know.

Is Depression a Zelnorm Side Effect?

There are several possible side effects for people taking Zelnorm® (tegaserod maleate). Depression does appear to be one of the rare side effects reported in Zelnorm clinical studies.
Depression is a complaint that is reported rarely (less than 1 percent) in people taking Zelnorm. This data comes from clinical trials that studied Zelnorm extensively in thousands of people and documented its side effects. The challenge with Zelnorm and depression is that, given how uncommonly depression is reported with Zelnorm and how common it is within the general population, it is difficult to tell whether depression is actually caused by Zelnorm, other factors, or a combination of both.

Zelnorm and Depression: What Should You Look For?

Depression is extremely common in society today. In fact, in any given one-year period, 9.5 percent of the population (about 18.8 million American adults) suffers from depression. Therefore, knowing the symptoms of depression can be helpful.
Possible depression symptoms may include:
  • A persistent sad, anxious, or "empty" mood
  • Feelings of hopelessness and pessimism
  • Feelings of guilt, worthlessness, and helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy, fatigue, and being "slowed down"
  • Difficulty concentrating, remembering, and making decisions
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite and/or weight loss or overeating and weight gain
  • Thoughts of death or suicide and suicide attempts
  • Restlessness and irritability
  • Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain.
Keep in mind that there are other conditions that can share similar symptoms with depression.
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Zelnorm Information

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