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Zelnorm Drug Interactions

When oral contraceptives or digoxin are taken together with Zelnorm, drug interactions may potentially occur. The drug interactions can cause a slight decrease in the levels of digoxin or oral contraceptive in your blood. For most people, these drug interactions do not cause any problems, and the dosages do not need to be adjusted.

Zelnorm Drug Interactions: An Overview

Zelnorm® (tegaserod maleate) is unlikely to interact with most medications. For the few medications that do interact with Zelnorm, the interaction is not severe enough to require any change in dosages. These medications that might interact with Zelnorm include:


In March 2007, Zelnorm was taken off the market in the United States because it was shown to increase the risk for a heart attack, angina, or stroke. In July 2007, the United States Food and Drug Administration (FDA) announced that Zelnorm will be available to people who meet certain criteria through a special program called a "treatment IND" (see Zelnorm Recall for more information). However, as of April 2, 2008, Zelnorm is no longer available under the treatment IND program, although it may still be available in certain emergency situations.

Zelnorm Interactions Explained

Digoxin (Digitek, Lanoxin)
Taking Zelnorm with digoxin can slightly decrease the level of digoxin your blood. For most people, this interaction will not cause any problems, and the doses of these medications do not need to be adjusted.

Zelnorm Information

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