Zelnorm Warnings and Precautions
Some warnings and precautions with Zelnorm to be aware of include:
- Zelnorm can cause very severe diarrhea. Severe diarrhea (or diarrhea that lasts a long time) can be dangerous, causing severe dehydration, low blood pressure (hypotension), and fainting. In studies, some people who took Zelnorm had diarrhea severe enough to require hospitalization. If you have severe diarrhea while taking Zelnorm, contact your healthcare provider right away.
- Zelnorm can interact with certain other medications (see Zelnorm Drug Interactions).
- Zelnorm is considered a pregnancy Category B medication. This means that Zelnorm is probably safe for use during pregnancy. However, because Zelnorm has not been studied in pregnant women, the full risks of using Zelnorm during pregnancy are not known. Women who are pregnant should take Zelnorm only if the benefits of Zelnorm outweigh the possible risks to the developing baby. Before taking Zelnorm during pregnancy, be sure to talk with your healthcare provider about Zelnorm's possible risks and benefits, as well as other ways to relieve IBS and constipation during pregnancy (see Zelnorm During Pregnancy for more information).
- It is not known if Zelnorm is passed through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about the safety of taking Zelnorm while breastfeeding. He or she can decide whether taking Zelnorm while nursing would be okay for your particular situation.
- Contact your healthcare provider right away if you have new or sudden worsening of abdominal pain (or stomach pain) while taking Zelnorm.
- Zelnorm has been reported to cause ischemic colitis, a dangerous condition involving decreased blood flow to the large intestine. If ischemic colitis is severe or lasts too long, the parts of the intestine that are not getting enough blood may be severely damaged. Contact your healthcare provider right away if you have new or sudden worsening of abdominal pain (or stomach pain), rectal bleeding, or bloody diarrhea. These can be signs of ischemic colitis.